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Ketoconazole (base)
- 英文名称：Ketoconazole (base)
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10009
- cas：65277-42-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10009 |
| 用途 | 科研检测 |
| 英文名称 | Ketoconazole (base) |
| 包装规格 | 1MG |
| CAS编号 | 65277-42-1 |
| 别名 | Ketoconazole (base) |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by TLC
分子式:C26H28Cl2N4O4
分子量:531.43
溶剂:DMSO (25 mg/ml); Ethanol (20 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Cytochrome P450 inhibitor
Function / Pharmacology:Ketoconazole is a broad spectrum antifungal agent which acts via inhibition of a cytochrome P450, CYP51A1 which is a lanosterol 14?-demethylase.1 Also inhibits CYP3A and CYP1A1.2 Inhibits adrenal steroidogenesis.3 Downregulates cholesterol synthesis in drug-tolerant human lung cancer cell lines.4 Blocks the biosynthesis of leukotrienes (LT) via inhibition of 5-lipoxygenase and dose dependently inhibits LT-mediated bronchoconstriction in guinea pigs.5
分子式:C26H28Cl2N4O4
分子量:531.43
溶剂:DMSO (25 mg/ml); Ethanol (20 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Cytochrome P450 inhibitor
Function / Pharmacology:Ketoconazole is a broad spectrum antifungal agent which acts via inhibition of a cytochrome P450, CYP51A1 which is a lanosterol 14?-demethylase.1 Also inhibits CYP3A and CYP1A1.2 Inhibits adrenal steroidogenesis.3 Downregulates cholesterol synthesis in drug-tolerant human lung cancer cell lines.4 Blocks the biosynthesis of leukotrienes (LT) via inhibition of 5-lipoxygenase and dose dependently inhibits LT-mediated bronchoconstriction in guinea pigs.5
