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GW-5074
- 英文名称:GW-5074
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10025
- cas:220904-83-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10025 |
用途 | 科研检测 |
英文名称 | GW-5074 |
包装规格 | 1MG |
CAS编号 | 220904-83-6 |
别名 | GW-5074 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC NMR conforms
分子式:C15H8Br2INO2
分子量:520.95
溶剂:DMSO (50 mg/ml)
性状:Dark orange solid MP = 267-268°C
存储:-20°C
Activity (short version):c-Raf1 inhibitor
Function / Pharmacology:Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.
分子式:C15H8Br2INO2
分子量:520.95
溶剂:DMSO (50 mg/ml)
性状:Dark orange solid MP = 267-268°C
存储:-20°C
Activity (short version):c-Raf1 inhibitor
Function / Pharmacology:Potent inhibitor of cRAF1 kinase (IC50 = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.