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LFM-A13
- 英文名称：LFM-A13
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10026
- cas：244240-24-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10026 |
| 用途 | 科研检测 |
| 英文名称 | LFM-A13 |
| 包装规格 | 1MG |
| CAS编号 | 244240-24-2 |
| 别名 | LFM-A13 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C11H8Br2N2O2
分子量:360.00
溶剂:DMSO (15 mg/ml) Ethanol (15 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):BTK inhibitor
Function / Pharmacology:LFM-A13 is a selective inhibitor of Bruton’s tyrosine kinase (BTK) – IC50’s = 2.5 μM (recombinant BTK) and 17.2 μM (human BTK).1,2 It has also been shown to inhibit Polo-ilke kinase (PLK) – IC50 = 61 μM for human PLK3.3 It displayed no activity (concentrations up to 278 μM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten tyrosine kinases3.
分子式:C11H8Br2N2O2
分子量:360.00
溶剂:DMSO (15 mg/ml) Ethanol (15 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):BTK inhibitor
Function / Pharmacology:LFM-A13 is a selective inhibitor of Bruton’s tyrosine kinase (BTK) – IC50’s = 2.5 μM (recombinant BTK) and 17.2 μM (human BTK).1,2 It has also been shown to inhibit Polo-ilke kinase (PLK) – IC50 = 61 μM for human PLK3.3 It displayed no activity (concentrations up to 278 μM) at JAK1, JAK3, HCK, EGFRK and IRK2 or CDK1-3, CHK1, IKK, MAPK1, SAPK2a and ten tyrosine kinases3.
