纯度:98% by TLC [ 10 methanol in methylene chloride + 0.1% NH4OH; Rf = 0.43];NMR (Conforms)
分子式:C25H41NO2 ? HCl
分子量:387.61 ? 36.46
溶剂:Water (30 mg/ml), DMSO (30 mg/ml)
性状:White or off-white solid
存储:RT
Activity (short version):Cholesterol transport inhibitor
Function / Pharmacology:U18666A is an oxidosqualene reductase inhibitor.1 Inhibits the egress of cholesterol from late endosomes and lysosomes.2 Also used to study Niemann-Pick disease and for assessing the importance of molecular trafficking through the lysosomal pathway in other conditions.3