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Zileuton
- 英文名称：Zileuton
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10084
- cas：111406-87-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-10-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10084 |
| 用途 | 科研检测 |
| 英文名称 | Zileuton |
| 包装规格 | 1MG |
| CAS编号 | 111406-87-2 |
| 别名 | Zileuton |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98%,;NMR (Conforms)
分子式:C11H12N2O2S
分子量:236.29
溶剂:DMSO (25 mg/ml)
性状:white solid
存储:-20°C
Activity (short version):5-LO inhibitor
Function / Pharmacology:Zileuton is a reversible inhibitor (IC50 = 500nM RBL-1 cells, 300nM rat PMNL cells) of 5-Lipoxygenase (5-LO).1 It also inhibited leukotriene B4 biosynthesis (IC50’s = 400nM rat PMNL, 400nM human PMNL and 900nM human whole blood).1 Zileuton suppressed prostaglandin biosynthesis via interference with arachidonic acid release in macrophages independent of 5-LO inhibition (IC50 = 13 μM PGE2 inhibition in LPS-stimulated whole blood).2 Zileuton was approved by the FDA in 1997 for the treatment of asthma (ZYFLO).
分子式:C11H12N2O2S
分子量:236.29
溶剂:DMSO (25 mg/ml)
性状:white solid
存储:-20°C
Activity (short version):5-LO inhibitor
Function / Pharmacology:Zileuton is a reversible inhibitor (IC50 = 500nM RBL-1 cells, 300nM rat PMNL cells) of 5-Lipoxygenase (5-LO).1 It also inhibited leukotriene B4 biosynthesis (IC50’s = 400nM rat PMNL, 400nM human PMNL and 900nM human whole blood).1 Zileuton suppressed prostaglandin biosynthesis via interference with arachidonic acid release in macrophages independent of 5-LO inhibition (IC50 = 13 μM PGE2 inhibition in LPS-stimulated whole blood).2 Zileuton was approved by the FDA in 1997 for the treatment of asthma (ZYFLO).
