|
Aclacinomycin A HCl
- 英文名称：Aclacinomycin A HCl
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10085
- cas：75443-99-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10085 |
| 用途 | 科研检测 |
| 英文名称 | Aclacinomycin A HCl |
| 包装规格 | 1MG |
| CAS编号 | 75443-99-1 |
| 别名 | Aclacinomycin A HCl |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:95% by TLC, NMR Conforms
分子式:C42H53NO15 HCl
分子量:848.33
溶剂:DMSO (30 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Proteasome inhibitor
Function / Pharmacology:Specific inhibitor of the 20S proteasome chymotrypsin-like activity1. Inhibition of Brg1 proteasomal degradation by aclacinomycin A reverses (0.25 μM in ILU-18 cells ) the removal of Brg1 from promoters of inflammatory genes elucidating the regulatory role of the proteasome in controlling the duration of the inflammatory process2. Induces the differentiation of K562 cells towards the erythroid pathway3. Induces apoptosis4. Cell permeable.
分子式:C42H53NO15 HCl
分子量:848.33
溶剂:DMSO (30 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Proteasome inhibitor
Function / Pharmacology:Specific inhibitor of the 20S proteasome chymotrypsin-like activity1. Inhibition of Brg1 proteasomal degradation by aclacinomycin A reverses (0.25 μM in ILU-18 cells ) the removal of Brg1 from promoters of inflammatory genes elucidating the regulatory role of the proteasome in controlling the duration of the inflammatory process2. Induces the differentiation of K562 cells towards the erythroid pathway3. Induces apoptosis4. Cell permeable.
