纯度:98% by TLC, NMR Conforms
分子式:C35H30N4O4
分子量:570.65
溶剂:DMSO (15 mg/ml) Ethanol (2 mg/ml)
性状:White solid
存储:RT
Activity (short version):Protein kinase inhib (pan spec.)
Function / Pharmacology:Broad spectrum kinase inhibitor. Inhibited kinases include, but are not limited to; PKA, PKC, S6 Kinase, KDR, PKC, Akt, EGFR, VEGFR, PDGFR, c-kit, and FLT-3. Acute myeloid leukemia related mutant forms of FLT-3 are also inhibited both in vitro and in vivo. PKC-412 has been demonstrated to induce apoptosis and shows broad antiproliferative activity in various tumor cell lines. Cell Permeable