纯度:98% by TLC;NMR (Conforms)
分子式:C21H22ClNO3
分子量:371.86
溶剂:DMSO (25 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Phospholipase A2 inhibitor
Function / Pharmacology:Reversible inhibitor of Ca2+-independent phospholipase A2 (PLA2), IC50=7 ?M for guinea pig lung PLA2.1 Inhibits epinephrine-induced thromboxane production in platelets.1 Inhibition of PLA2 by ONO-RS-032 disrupts endosome tubule formation and maintenance of the Golgi complex.2-4 Prevents Xenopus oocyte maturation at stage V.5