纯度:>98% [TLC 40% ethanol in hexanes; Rf = 0.31]
分子式:C22H21NO3
分子量:347.42
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):GPR40 agonist
Function / Pharmacology:Selective agonist at the free fatty acid receptor, FFA1/4, (GPR40 and GPR120).1 Displays anti-allodynic and anti-hyperalgesic effects in mouse inflammatory and neuropathic pain models.2 Inhibits LPA-induced proliferation of DU145 and PC-3 cells.3 Decreases hepatic lipid accumulation in a high fat diet steatosis mouse model.4 Promotes brown adipose tissue thermogenesis.5