纯度:98% by HPLC;NMR (Conforms)
分子式:C30H44N6O2·2HCl
分子量:593.63
溶剂:Water (30 mg/ml) Ethanol (50 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Antioxidant lazaroid
Function / Pharmacology:U-83826E is a trolox-derived antioxidant lazaroid. Mitigates the toxic effects of methanol on antioxidant systems in rat brain.1 Prevents pro-oxidant-induced death of dopaminergic neurons.2 Improves viability of endothelial cells after H2O2-induced oxidative stress.3 Improves outcome markers in a rat hemorrhagic shock model and increases expression of HSP72.4