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Necrostatin-1
- 英文名称:Necrostatin-1
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10133
- cas:4311-88-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10133 |
用途 | 科研检测 |
英文名称 | Necrostatin-1 |
包装规格 | 1MG |
CAS编号 | 4311-88-0 |
别名 | Necrostatin-1 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC [5% methanol in methylene chloride, Rf = 0.37] NMR Conforms
分子式:C13H13N3OS
分子量:259.33
溶剂:DMSO (20 mg/ml) Ethanol (5 mg/ml)
性状:Pale yellow solid
存储:RT
Activity (short version):Necroptosis inhibitor
Function / Pharmacology:Necrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM).1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM).2 It displays a protective effect in a mouse model of ischemic brain injury1, inhibits myocardial cell death and reduces infarct size in various mouse heart models3 and inhibits glutamate-induced oxytosis in HT-22 cells4.
分子式:C13H13N3OS
分子量:259.33
溶剂:DMSO (20 mg/ml) Ethanol (5 mg/ml)
性状:Pale yellow solid
存储:RT
Activity (short version):Necroptosis inhibitor
Function / Pharmacology:Necrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM).1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM).2 It displays a protective effect in a mouse model of ischemic brain injury1, inhibits myocardial cell death and reduces infarct size in various mouse heart models3 and inhibits glutamate-induced oxytosis in HT-22 cells4.