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Necrostatin-1
- 英文名称：Necrostatin-1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10133
- cas：4311-88-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10133 |
| 用途 | 科研检测 |
| 英文名称 | Necrostatin-1 |
| 包装规格 | 1MG |
| CAS编号 | 4311-88-0 |
| 别名 | Necrostatin-1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC [5% methanol in methylene chloride, Rf = 0.37] NMR Conforms
分子式:C13H13N3OS
分子量:259.33
溶剂:DMSO (20 mg/ml) Ethanol (5 mg/ml)
性状:Pale yellow solid
存储:RT
Activity (short version):Necroptosis inhibitor
Function / Pharmacology:Necrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM).1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM).2 It displays a protective effect in a mouse model of ischemic brain injury1, inhibits myocardial cell death and reduces infarct size in various mouse heart models3 and inhibits glutamate-induced oxytosis in HT-22 cells4.
分子式:C13H13N3OS
分子量:259.33
溶剂:DMSO (20 mg/ml) Ethanol (5 mg/ml)
性状:Pale yellow solid
存储:RT
Activity (short version):Necroptosis inhibitor
Function / Pharmacology:Necrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM).1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM).2 It displays a protective effect in a mouse model of ischemic brain injury1, inhibits myocardial cell death and reduces infarct size in various mouse heart models3 and inhibits glutamate-induced oxytosis in HT-22 cells4.
