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A-769662
- 英文名称：A-769662
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10140
- cas：844499-71-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10140 |
| 用途 | 科研检测 |
| 英文名称 | A-769662 |
| 包装规格 | 1MG |
| CAS编号 | 844499-71-4 |
| 别名 | A-769662 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C20H12N2O3S
分子量:360.39
溶剂:DMSO (30 mg/ml) Ethanol (5 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):AMPK activator
Function / Pharmacology:A potent and reversible AMP-activated protein kinase (AMPK) allosteric activator. Activates AMPK by binding to the ? and ? subunits and not the AMP binding site1. EC50=0.8 ?M for purified rat liver AMPK and inhibits fatty acid biosynthesis in rat hepatocytes IC50=3.2 ?M2. Inhibits the rate of whole-body fatty acid oxidation, decreases body weight gain, reduces plasma and liver triglycerides and lowers plasma glucose in ob/ob mice2. Inhibits adipocyte differentiation3. Prevents transcriptional activation of Oct4 and establishes a metabolic barrier to induced pluripotent stem cell reprogramming4. Synergizes with AICAR5. Cell permeable.
分子式:C20H12N2O3S
分子量:360.39
溶剂:DMSO (30 mg/ml) Ethanol (5 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):AMPK activator
Function / Pharmacology:A potent and reversible AMP-activated protein kinase (AMPK) allosteric activator. Activates AMPK by binding to the ? and ? subunits and not the AMP binding site1. EC50=0.8 ?M for purified rat liver AMPK and inhibits fatty acid biosynthesis in rat hepatocytes IC50=3.2 ?M2. Inhibits the rate of whole-body fatty acid oxidation, decreases body weight gain, reduces plasma and liver triglycerides and lowers plasma glucose in ob/ob mice2. Inhibits adipocyte differentiation3. Prevents transcriptional activation of Oct4 and establishes a metabolic barrier to induced pluripotent stem cell reprogramming4. Synergizes with AICAR5. Cell permeable.
