纯度:98% by TLC,;NMR (Conforms)
分子式:C16H15N3O3 · HCl
分子量:333.78
溶剂:DMSO (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):JAK3 inhibitor
Function / Pharmacology:JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion.1 Increases survival in a mouse ALS model.2 Delays or prevents autoimmune type 1 diabetes in NOD mice.3 Exhibits potent anti-inflammatory activity in mouse models of peritonitis, colitis, cellulitis and systemic inflammatory response syndrome.4 Displays protective effects against myocardial ischemia and reperfusion injury in mouse models.5