|
GSK-1016790A
- 英文名称：GSK-1016790A
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10162
- cas：942206-85-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10162 |
| 用途 | 科研检测 |
| 英文名称 | GSK-1016790A |
| 包装规格 | 1MG |
| CAS编号 | 942206-85-1 |
| 别名 | GSK-1016790A |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C28H32Cl2N4O6S2
分子量:655.62
溶剂:DMSO (10 mg/ml)
性状:white solid
存储:-20°C
Activity (short version):TRPV4 channel blocker
Function / Pharmacology:A novel and potent TRPV4 channel agonist. GSK1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300-fold more potent than 4α-PDD and is a valuable tool for investigating the role of TRPV4 in physiological processes.
分子式:C28H32Cl2N4O6S2
分子量:655.62
溶剂:DMSO (10 mg/ml)
性状:white solid
存储:-20°C
Activity (short version):TRPV4 channel blocker
Function / Pharmacology:A novel and potent TRPV4 channel agonist. GSK1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300-fold more potent than 4α-PDD and is a valuable tool for investigating the role of TRPV4 in physiological processes.
