纯度:98% by TLC;NMR (Conforms)
分子式:C25H34O6
分子量:460.53
溶剂:DMSO (5 mg/ml) Ethanol (4 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PKC activator
Function / Pharmacology:Selective activator of protein kinase C which displays antileukemic activity mediated via PKC??1 In contrast, it provides a strong survival signal to resting and activated human T cells via activation of PKC and downstream activation of NF?B.2 Treatment of subcutaneous tumors results in anti-cancer CD8 T cells, also displays adjuvant activity and synergizes with cancer immunotherapies.3 Induces senescence-like growth arrest in solid tumor cells.4 Inhibits HIV-1 infection at an early pathway of viral entry.5