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CHIR-99021
- 英文名称:CHIR-99021
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10195
- cas:252917-06-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10195 |
用途 | 科研检测 |
英文名称 | CHIR-99021 |
包装规格 | 1MG |
CAS编号 | 252917-06-9 |
别名 | CHIR-99021 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:99% by TLC,;NMR (Conforms)
分子式:C22H18Cl2N8
分子量:465.35
溶剂:DMSO (25 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):GSK3β inhibitor
Function / Pharmacology:Potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells2. Promotes replication and survival of pancreatic beta cells3. Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors4. Cell permeable and active in vivo.
分子式:C22H18Cl2N8
分子量:465.35
溶剂:DMSO (25 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):GSK3β inhibitor
Function / Pharmacology:Potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM)1. Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells2. Promotes replication and survival of pancreatic beta cells3. Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors4. Cell permeable and active in vivo.