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A83-01
- 英文名称：A83-01
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10234
- cas：909910-43-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10234 |
| 用途 | 科研检测 |
| 英文名称 | A83-01 |
| 包装规格 | 1MG |
| CAS编号 | 909910-43-6 |
| 别名 | A83-01 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C25H19N5S
分子量:421.53
溶剂:DMSO (20 mg/ml)
性状:Light yellow solid
存储:-20°C
Activity (short version):ALK inhibitor
Function / Pharmacology:Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo.
分子式:C25H19N5S
分子量:421.53
溶剂:DMSO (20 mg/ml)
性状:Light yellow solid
存储:-20°C
Activity (short version):ALK inhibitor
Function / Pharmacology:Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo.
