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A83-01
- 英文名称:A83-01
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10234
- cas:909910-43-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10234 |
用途 | 科研检测 |
英文名称 | A83-01 |
包装规格 | 1MG |
CAS编号 | 909910-43-6 |
别名 | A83-01 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C25H19N5S
分子量:421.53
溶剂:DMSO (20 mg/ml)
性状:Light yellow solid
存储:-20°C
Activity (short version):ALK inhibitor
Function / Pharmacology:Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo.
分子式:C25H19N5S
分子量:421.53
溶剂:DMSO (20 mg/ml)
性状:Light yellow solid
存储:-20°C
Activity (short version):ALK inhibitor
Function / Pharmacology:Potent and selective ALK4, 5 and 7 inhibitor1,2. IC50=45, 12 and 7.5 nM respectively. Prevents phosphorylation of Smad2/3 and growth inhibition induced by TGFβ2. Inhibits differentiation of rat induced pluripotent stem cells and increases clonal expansion efficiency3. Together with AMI-5, A83-01 enabled Oct4-induced reprogramming of mouse embryonic fibroblasts4. Cell permeable. Active in vivo.