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FH-535
- 英文名称:FH-535
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10235
- cas:108409-83-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10235 |
用途 | 科研检测 |
英文名称 | FH-535 |
包装规格 | 1MG |
CAS编号 | 108409-83-2 |
别名 | FH-535 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C13H10Cl2N2O4S
分子量:361.21
溶剂:DMSO (25 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):Wnt/β-cantenin inhibitor
Function / Pharmacology:Suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators β-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4.
分子式:C13H10Cl2N2O4S
分子量:361.21
溶剂:DMSO (25 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):Wnt/β-cantenin inhibitor
Function / Pharmacology:Suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators β-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4.