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BIX-01294
- 英文名称:BIX-01294
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10241
- cas:935693-62-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10241 |
用途 | 科研检测 |
英文名称 | BIX-01294 |
包装规格 | 1MG |
CAS编号 | 935693-62-2 |
别名 | BIX-01294 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC
分子式:C28H38N6O2
分子量:600.02
溶剂:Water (50 mg/ml) DMSO (50 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Histone Methyl transferase inhibitor+D257
Function / Pharmacology:BIX-01294 is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 μM) as well as GLP HMTase (IC50 = 38 μM) leading to a decrease in H3K9me2(histone H3 lysine 9 methylation) in vitro.1 BIX-01294 facilitates the reactivation of pluripotency genes and induces passive demethylation, thus promoting reprogramming. BIX-01294, in combination with BAY K8644 (a calcium channel agonist), was found to improve reprogramming efficiencies of Oct4-Klf4-(OK)-infected neural progenitor cells.3
分子式:C28H38N6O2
分子量:600.02
溶剂:Water (50 mg/ml) DMSO (50 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Histone Methyl transferase inhibitor+D257
Function / Pharmacology:BIX-01294 is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 μM) as well as GLP HMTase (IC50 = 38 μM) leading to a decrease in H3K9me2(histone H3 lysine 9 methylation) in vitro.1 BIX-01294 facilitates the reactivation of pluripotency genes and induces passive demethylation, thus promoting reprogramming. BIX-01294, in combination with BAY K8644 (a calcium channel agonist), was found to improve reprogramming efficiencies of Oct4-Klf4-(OK)-infected neural progenitor cells.3