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Garcinol
- 英文名称:Garcinol
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10243
- cas:78824-30-3
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10243 |
用途 | 科研检测 |
英文名称 | Garcinol |
包装规格 | 1MG |
CAS编号 | 78824-30-3 |
别名 | Garcinol |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>95%
分子式:C38H50O6
分子量:602.80
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):HAT inhibitor
Function / Pharmacology:Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7μM and PCAF IC50=5μM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2
分子式:C38H50O6
分子量:602.80
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):HAT inhibitor
Function / Pharmacology:Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7μM and PCAF IC50=5μM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2