纯度:98% by HPLC;NMR (Conforms)
分子式:C17H30N2O5
分子量:342.43
溶剂:DMSO (20 mg/ml) Ethanol (10 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Cysteine protease inhibitor
Function / Pharmacology:Cell-permeable derivative of E-64c, an inhibitor of calpain and other cysteine proteases, such as papain, cathepsin B and cathepsin L.1,2 Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the ethyl ester and reduce cell permeability. Typical working concentration is 0.5-10 μg/ml. Inhibits degradation of autophagic cargo inside autolysosomes3