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NSC663284
- 英文名称：NSC663284
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10256
- cas：383907-43-5
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-16
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10256 |
| 用途 | 科研检测 |
| 英文名称 | NSC663284 |
| 包装规格 | 1MG |
| CAS编号 | 383907-43-5 |
| 别名 | NSC663284 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C15H16ClN3O3
分子量:321.77
溶剂:DMSO (15 mg/ml) Ethanol (55 mg/ml)
性状:Red solid
存储:-20°C
Activity (short version):Cdc25 phosphatase inhibitor
Function / Pharmacology:Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.
分子式:C15H16ClN3O3
分子量:321.77
溶剂:DMSO (15 mg/ml) Ethanol (55 mg/ml)
性状:Red solid
存储:-20°C
Activity (short version):Cdc25 phosphatase inhibitor
Function / Pharmacology:Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B1. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation2. Inhibits the growth of a variety of human tumor cell lines3. Acts via irreversible oxidation of the catalytic cysteine of CDC254.
