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Wiskostatin
- 英文名称：Wiskostatin
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10257
- cas：253449-04-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10257 |
| 用途 | 科研检测 |
| 英文名称 | Wiskostatin |
| 包装规格 | 1MG |
| CAS编号 | 253449-04-6 |
| 别名 | Wiskostatin |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC [9:1 CH2Cl2/CH3OH Rf = 0.16];NMR (Conforms)
分子式:C17H18Br2N2O
分子量:426.15
溶剂:DMSO (30 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:RT
Activity (short version):N-WASP inhibitor
Function / Pharmacology:A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.
分子式:C17H18Br2N2O
分子量:426.15
溶剂:DMSO (30 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:RT
Activity (short version):N-WASP inhibitor
Function / Pharmacology:A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.
