![]() |
Wiskostatin
- 英文名称:Wiskostatin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10257
- cas:253449-04-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10257 |
用途 | 科研检测 |
英文名称 | Wiskostatin |
包装规格 | 1MG |
CAS编号 | 253449-04-6 |
别名 | Wiskostatin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC [9:1 CH2Cl2/CH3OH Rf = 0.16];NMR (Conforms)
分子式:C17H18Br2N2O
分子量:426.15
溶剂:DMSO (30 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:RT
Activity (short version):N-WASP inhibitor
Function / Pharmacology:A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.
分子式:C17H18Br2N2O
分子量:426.15
溶剂:DMSO (30 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:RT
Activity (short version):N-WASP inhibitor
Function / Pharmacology:A selective, reversible inhibitor of neural Wiskott-Aldrich syndrome protein (N-WASP) activity1. Binds to the regulatory domain of N-WASP and inhibits activation of Arp2/3 complex by forcing N-WASP into an inactive conformation2. Inhibits PIP2-induced actin polymerization (EC50=4 μM). Perturbs agrin-elicited acetylcholine receptor clustering3. Inhibits the formation of dendritic spines and synapses in hippocampal neurons4.