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SMI-4a
- 英文名称:SMI-4a
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10262
- cas:438190-29-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10262 |
用途 | 科研检测 |
英文名称 | SMI-4a |
包装规格 | 1MG |
CAS编号 | 438190-29-5 |
别名 | SMI-4a |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C11H6F3NO2S
分子量:273.23
溶剂:DMSO (100 mg/ml) Ethanol (40 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):PIM1 inhibitor
Function / Pharmacology:A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive3. A useful tool for exploring the involvement of Pim in cellular signaling4. Cell permeable.
分子式:C11H6F3NO2S
分子量:273.23
溶剂:DMSO (100 mg/ml) Ethanol (40 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):PIM1 inhibitor
Function / Pharmacology:A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively). Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive3. A useful tool for exploring the involvement of Pim in cellular signaling4. Cell permeable.