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FQI1
- 英文名称:FQI1
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10263
- cas:599151-35-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10263 |
用途 | 科研检测 |
英文名称 | FQI1 |
包装规格 | 1MG |
CAS编号 | 599151-35-6 |
别名 | FQI1 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C18H17NO4
分子量:311.33
溶剂:DMSO (50 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):LSF inhibitor
Function / Pharmacology:Inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 ?M). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2 In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3 Blocks LSF-stimulated activation of DNA methyltransferase 1.4 Cell permeable.
分子式:C18H17NO4
分子量:311.33
溶剂:DMSO (50 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):LSF inhibitor
Function / Pharmacology:Inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 ?M). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2 In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3 Blocks LSF-stimulated activation of DNA methyltransferase 1.4 Cell permeable.