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Spautin-1
- 英文名称：Spautin-1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10269
- cas：1262888-28-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10269 |
| 用途 | 科研检测 |
| 英文名称 | Spautin-1 |
| 包装规格 | 1MG |
| CAS编号 | 1262888-28-7 |
| 别名 | Spautin-1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C15H11F2N3
分子量:271.27
溶剂:DMSO (50 mg/ml) Ethanol (15 mg/ml with warming)
性状:Tan solid
存储:-20°C
Activity (short version):Inhibits autophagy by inhibiting USP 10 and 13
Function / Pharmacology:A specific and potent autophagy inhibitor. Spautin-1 promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific proteases USP10 and USP13 which target the Beclin-1 subunit of Vps34 complexes1. Deranges dengue virion maturation2. Inhibits autophagy in a Beclin-1 independent manner in primary epithelial ovarian cancer cells3. Selectively induces cell death of mutant p53-expressing cancer cell lines under confluency4. Cell permeable.
分子式:C15H11F2N3
分子量:271.27
溶剂:DMSO (50 mg/ml) Ethanol (15 mg/ml with warming)
性状:Tan solid
存储:-20°C
Activity (short version):Inhibits autophagy by inhibiting USP 10 and 13
Function / Pharmacology:A specific and potent autophagy inhibitor. Spautin-1 promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin-specific proteases USP10 and USP13 which target the Beclin-1 subunit of Vps34 complexes1. Deranges dengue virion maturation2. Inhibits autophagy in a Beclin-1 independent manner in primary epithelial ovarian cancer cells3. Selectively induces cell death of mutant p53-expressing cancer cell lines under confluency4. Cell permeable.
