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Epoxomicin
- 英文名称：Epoxomicin
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10281
- cas：134381-21-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10281 |
| 用途 | 科研检测 |
| 英文名称 | Epoxomicin |
| 包装规格 | 1MG |
| CAS编号 | 134381-21-8 |
| 别名 | Epoxomicin |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:97% by HPLC,;NMR (Conforms)
分子式:C28H50N4O7
分子量:554.73
溶剂:DMSO (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Irreversible 20S proteasome inhibitor
Function / Pharmacology:Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome.1 It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 μM.1 Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells.2 Epoxomicin caused a progressive model of Parkinson’s disease in various systems.3,4,5 This model has been disputed.6,7
分子式:C28H50N4O7
分子量:554.73
溶剂:DMSO (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Irreversible 20S proteasome inhibitor
Function / Pharmacology:Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome.1 It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 μM.1 Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells.2 Epoxomicin caused a progressive model of Parkinson’s disease in various systems.3,4,5 This model has been disputed.6,7
