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Epoxomicin
- 英文名称:Epoxomicin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10281
- cas:134381-21-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10281 |
用途 | 科研检测 |
英文名称 | Epoxomicin |
包装规格 | 1MG |
CAS编号 | 134381-21-8 |
别名 | Epoxomicin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:97% by HPLC,;NMR (Conforms)
分子式:C28H50N4O7
分子量:554.73
溶剂:DMSO (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Irreversible 20S proteasome inhibitor
Function / Pharmacology:Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome.1 It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 μM.1 Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells.2 Epoxomicin caused a progressive model of Parkinson’s disease in various systems.3,4,5 This model has been disputed.6,7
分子式:C28H50N4O7
分子量:554.73
溶剂:DMSO (10 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Irreversible 20S proteasome inhibitor
Function / Pharmacology:Epoxomicin is a potent, selective and cell permeable irreversible inhibitor of the 20S proteasome.1 It does not inhibit non-proteasomal proteases such as papain, chymotrypsin, trypsin, calpain and cathepsin B at concentrations up to 50 μM.1 Epoxomicin was isolated from Actinomycete strain Q996-17 and displayed in vivo antitumor activity against B16 melanoma cells.2 Epoxomicin caused a progressive model of Parkinson’s disease in various systems.3,4,5 This model has been disputed.6,7