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BI-6015
- 英文名称：BI-6015
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10295
- cas：93987-29-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10295 |
| 用途 | 科研检测 |
| 英文名称 | BI-6015 |
| 包装规格 | 1MG |
| CAS编号 | 93987-29-2 |
| 别名 | BI-6015 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C15H13N3O4S
分子量:331.35
溶剂:DMSO (25 mg/ml) Ethanol (10 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):HNF4α inhibitor
Function / Pharmacology:Hepatocyte nuclear factor 4α (HNF4α) antagonist. HNF4α is a central regulator of gene expression in cell types that play a central role in metabolic homeostasis. 1 BI-6015 binds to HNF4α with high affinity and modulates the expression of known target genes. It was shown to be selectively cytotoxic to cancer cell lines in vitro and in vivo however in vivo potency was limited by suboptimal pharmacokinetics. 2 Represents the first small molecule tool for pharmacologic modulation of HNF4α activity. 2 Cell permeable.
分子式:C15H13N3O4S
分子量:331.35
溶剂:DMSO (25 mg/ml) Ethanol (10 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):HNF4α inhibitor
Function / Pharmacology:Hepatocyte nuclear factor 4α (HNF4α) antagonist. HNF4α is a central regulator of gene expression in cell types that play a central role in metabolic homeostasis. 1 BI-6015 binds to HNF4α with high affinity and modulates the expression of known target genes. It was shown to be selectively cytotoxic to cancer cell lines in vitro and in vivo however in vivo potency was limited by suboptimal pharmacokinetics. 2 Represents the first small molecule tool for pharmacologic modulation of HNF4α activity. 2 Cell permeable.
