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BMS-303141
- 英文名称:BMS-303141
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10306
- cas:943962-47-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10306 |
用途 | 科研检测 |
英文名称 | BMS-303141 |
包装规格 | 1MG |
CAS编号 | 943962-47-8 |
别名 | BMS-303141 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C19H15Cl2NO4S
分子量:424.30
溶剂:DMSO (25 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):ATP citrate lyase (ACL) inhibitor
Function / Pharmacology:Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 ?M. Inhibits lipid biosynthesis, IC50=8 ?M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4
分子式:C19H15Cl2NO4S
分子量:424.30
溶剂:DMSO (25 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):ATP citrate lyase (ACL) inhibitor
Function / Pharmacology:Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 ?M. Inhibits lipid biosynthesis, IC50=8 ?M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4