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NSC697923
- 英文名称：NSC697923
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10308
- cas：343351-67-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10308 |
| 用途 | 科研检测 |
| 英文名称 | NSC697923 |
| 包装规格 | 1MG |
| CAS编号 | 343351-67-7 |
| 别名 | NSC697923 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C11H9NO5S
分子量:267.26
溶剂:DMSO (25 mg/ml) Ethanol (5 mg/ml)
性状:pink solid
存储:-20°C
Activity (short version):Ubiquitin E2 Conjugating enzyme inhibitor
Function / Pharmacology:Selective inhibitor of E2 ubiquitin-conjugating enzyme, Ubc13-Uev1A. Does not inhibit UbcH5c activity. Impedes the formation of the Ubc13 and inhibits NF-κB activation in activated B cell-like diffuse large B-cell lymphoma (ABC-DLBCL) cells1. Blocks proliferation and survival of both ABC-DLBCL and germinal center B cell-like (GCB)-DLBCL cell lines, and survival of primary DLBCL cells. Acts via covalent bonding to E2 active site thiol2,3. Induces neuroblastoma cell death via activation of p53 and JNK4.
分子式:C11H9NO5S
分子量:267.26
溶剂:DMSO (25 mg/ml) Ethanol (5 mg/ml)
性状:pink solid
存储:-20°C
Activity (short version):Ubiquitin E2 Conjugating enzyme inhibitor
Function / Pharmacology:Selective inhibitor of E2 ubiquitin-conjugating enzyme, Ubc13-Uev1A. Does not inhibit UbcH5c activity. Impedes the formation of the Ubc13 and inhibits NF-κB activation in activated B cell-like diffuse large B-cell lymphoma (ABC-DLBCL) cells1. Blocks proliferation and survival of both ABC-DLBCL and germinal center B cell-like (GCB)-DLBCL cell lines, and survival of primary DLBCL cells. Acts via covalent bonding to E2 active site thiol2,3. Induces neuroblastoma cell death via activation of p53 and JNK4.
