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CZC-54252
- 英文名称：CZC-54252
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10310
- cas：1191911-27-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10310 |
| 用途 | 科研检测 |
| 英文名称 | CZC-54252 |
| 包装规格 | 1MG |
| CAS编号 | 1191911-27-9 |
| 别名 | CZC-54252 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C22H25ClN6O4S · HCl
分子量:541.46
溶剂:DMSO (50 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):LRRK2
Function / Pharmacology:Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM)1. The G2019S mutant is a common mutation found in familial Parkinson’s disease patients2. Cell permeable.
分子式:C22H25ClN6O4S · HCl
分子量:541.46
溶剂:DMSO (50 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):LRRK2
Function / Pharmacology:Novel, potent and selective inhibitor of the leucine-rich repeat kinase-2 (LRRK2), IC50 = 1.28 nM. Also inhibits G2019S mutant LRRK2, IC50 = 1.85 nM1. Attenuates the neuronal damage elicited by the action of LRRK2 G2019S mutant in primary human neurons (EC50 = 1 nM)1. The G2019S mutant is a common mutation found in familial Parkinson’s disease patients2. Cell permeable.
