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AK-7
- 英文名称：AK-7
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10316
- cas：420831-40-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10316 |
| 用途 | 科研检测 |
| 英文名称 | AK-7 |
| 包装规格 | 1MG |
| CAS编号 | 420831-40-9 |
| 别名 | AK-7 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C19H21BrN2O3S
分子量:437.36
溶剂:DMSO (50 mg/ml) Ethanol (8 mg/ml)
性状:White solid
存储:RT
Activity (short version):SIRT2 inhibitor
Function / Pharmacology:A selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt31. It down regulates cholesterol biosynthesis genes in primary striatal neurons1. Displays neuroprotective effects in Huntington’s disease mouse models including improved motor function, extended survival and reduced brain atrophy all of which were associated with reduced aggregated mutant huntingtin2.
分子式:C19H21BrN2O3S
分子量:437.36
溶剂:DMSO (50 mg/ml) Ethanol (8 mg/ml)
性状:White solid
存储:RT
Activity (short version):SIRT2 inhibitor
Function / Pharmacology:A selective Sirt2 inhibitor (IC50=15.5 μM) which does not inhibit Sirt1 or Sirt31. It down regulates cholesterol biosynthesis genes in primary striatal neurons1. Displays neuroprotective effects in Huntington’s disease mouse models including improved motor function, extended survival and reduced brain atrophy all of which were associated with reduced aggregated mutant huntingtin2.
