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Bromo-PTC
- 英文名称:Bromo-PTC
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10319
- cas:443144-54-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10319 |
用途 | 科研检测 |
英文名称 | Bromo-PTC |
包装规格 | 1MG |
CAS编号 | 443144-54-5 |
别名 | Bromo-PTC |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C10H12BrN3S
分子量:286.20
溶剂:DMSO (40 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:RT
Activity (short version):Cruzain inhibitor
Function / Pharmacology:Cruzain is the major cysteine protease of Trypanosoma cruzi, the protozoan parasite responsible for American trypanosomiasis or Chagas’ disease. Cruzain is essential for the replication of the parasite and thus is a new target for antitrypanosomal chemotherapy. Bromo-PTC is a potent inhibitor of cruzain (IC50 = 100 nM) which exhibits trypanocidal activity in cultured host cells without toxicity1.
分子式:C10H12BrN3S
分子量:286.20
溶剂:DMSO (40 mg/ml) Ethanol (10 mg/ml)
性状:White solid
存储:RT
Activity (short version):Cruzain inhibitor
Function / Pharmacology:Cruzain is the major cysteine protease of Trypanosoma cruzi, the protozoan parasite responsible for American trypanosomiasis or Chagas’ disease. Cruzain is essential for the replication of the parasite and thus is a new target for antitrypanosomal chemotherapy. Bromo-PTC is a potent inhibitor of cruzain (IC50 = 100 nM) which exhibits trypanocidal activity in cultured host cells without toxicity1.