纯度:98% by TLC,;NMR (Conforms)
分子式:C22H17NO6S
分子量:391.44
溶剂:DMSO (35 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):LPA2 antagonist
Function / Pharmacology:Selective agonist of the lysophosphatidic acid - 2 (LPA2) receptor. Displays antiapoptotic activity.1 Rescues apoptotically condemned cells from death and injury caused by high-dose γ-irradiation in vitro and in vivo. Rescues mice from deadly levels of radiation when given 24 hours post-exposure.2 Activates the ERK1/2 prosurvival pathway.2