|
680C91
- 英文名称：680C91
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10328
- cas：163239-22-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-12-08
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10328 |
| 用途 | 科研检测 |
| 英文名称 | 680C91 |
| 包装规格 | 1MG |
| CAS编号 | 163239-22-3 |
| 别名 | 680C91 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C15H11FN2
分子量:238.27
溶剂:DMSO (20 mg/ml) Ethanol (10 mg/ml)
性状:Light brown solid
存储:-20°C
Activity (short version):Tryptophan 2,3-dioxygenase inhibitor
Function / Pharmacology:A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM)1,2. Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal2. TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine, an endogenous tumor promoting AHR ligand4.
分子式:C15H11FN2
分子量:238.27
溶剂:DMSO (20 mg/ml) Ethanol (10 mg/ml)
性状:Light brown solid
存储:-20°C
Activity (short version):Tryptophan 2,3-dioxygenase inhibitor
Function / Pharmacology:A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM)1,2. Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal2. TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine, an endogenous tumor promoting AHR ligand4.
