纯度:98% by TLC,;NMR (Conforms)
分子式:C15H13N3OS2
分子量:315.41
溶剂:DMSo (30 mg/ml)
性状:Tan solid
存储:-20°C
Activity (short version):TRPA1 channel activator
Function / Pharmacology:Reversible, photoactive TRPA1 activator. Optovin stimulates human TRPA1 channels and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM) and mice, in vivo. Photodetection is performed by sensory neurons expressing the TRPA1 cation channel which is activated via structure-dependent photochemical reactions with redox-sensitive cysteine residues.1