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Salirasib
- 英文名称:Salirasib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10342
- cas:162520-00-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10342 |
用途 | 科研检测 |
英文名称 | Salirasib |
包装规格 | 1MG |
CAS编号 | 162520-00-5 |
别名 | Salirasib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C22H30O2S
分子量:358.54
溶剂:DMSO (20 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:RT
Activity (short version):Ras inhibitor
Function / Pharmacology:Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 μM).7
分子式:C22H30O2S
分子量:358.54
溶剂:DMSO (20 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:RT
Activity (short version):Ras inhibitor
Function / Pharmacology:Salirasib is a synthetic farnesylcysteine mimetic that inhibits ras proteins1,2 via disruption of interactions between the S-Prenyl moiety of Ras and the membrane anchorage domains3. It has been investigated in the treatment of various cancers.4,5 HCC cells pretreated with salirasib were sensitized to TRAIL-induced apoptosis.6 Salirasib has also been shown to inhibit TRPA1 (EC50 = 1.3 μM).7