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NSC405020
- 英文名称：NSC405020
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10343
- cas：7497-07-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10343 |
| 用途 | 科研检测 |
| 英文名称 | NSC405020 |
| 包装规格 | 1MG |
| CAS编号 | 7497-07-6 |
| 别名 | NSC405020 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C12H15NCl2O
分子量:260.15
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):MT1-MMP inhibitor
Function / Pharmacology:Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 > 100 μM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
分子式:C12H15NCl2O
分子量:260.15
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):MT1-MMP inhibitor
Function / Pharmacology:Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 > 100 μM). Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3
