纯度:98% by TLC,;NMR (Conforms)
分子式:C17H17ClN2O5
分子量:364.79
溶剂:DMSO (100 mg/ml) Ethanol (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):AKT activator
Function / Pharmacology:Akt activator. Binds to the pleckstrin homology domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.1 A useful tool for studying the PI3K/Akt axis.2