|
ML297
- 英文名称：ML297
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10350
- cas：1443246-62-5
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-12-08
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10350 |
| 用途 | 科研检测 |
| 英文名称 | ML297 |
| 包装规格 | 1MG |
| CAS编号 | 1443246-62-5 |
| 别名 | ML297 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C17H14F2N4O
分子量:328.32
溶剂:DMSO (45 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):GIRK inhibitor
Function / Pharmacology:Selective GIRK ? (Kir3.1/3.2) channel activator, IC50 = 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively. Has no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels.1,2 Displays antiseizure activity2 and decreases anxiety-related behavior without sedative or addictive effects3. Reduces glucose- and IBMX-stimulated GLP-1 secretion with no effect on GIP in murine L and K cells.4 Brain penetrant.
分子式:C17H14F2N4O
分子量:328.32
溶剂:DMSO (45 mg/ml) Ethanol (20 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):GIRK inhibitor
Function / Pharmacology:Selective GIRK ? (Kir3.1/3.2) channel activator, IC50 = 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively. Has no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels.1,2 Displays antiseizure activity2 and decreases anxiety-related behavior without sedative or addictive effects3. Reduces glucose- and IBMX-stimulated GLP-1 secretion with no effect on GIP in murine L and K cells.4 Brain penetrant.
