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AI-1
- 英文名称：AI-1
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10352
- cas：75483-04-4
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10352 |
| 用途 | 科研检测 |
| 英文名称 | AI-1 |
| 包装规格 | 1MG |
| CAS编号 | 75483-04-4 |
| 别名 | AI-1 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C13H12ClNO3
分子量:265.70
溶剂:DMSO (15 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Nrf2 activator
Function / Pharmacology:A novel antioxidant response element (ARE) activator which activates Nrf2 by covalently modifying Keap1 (Kelch-like ECH-associated protein 1) a negative regulator of Nrf2. Modification of Cys151 of Keap1 by AI-1 disrupts the ability of Keap1 to searve as an adaptor for Cul3-Keap1 ubiquitin ligase complex, thereby stabilizing and inducing transcriptional activation of Nrf2. A useful pharmacological tool for probing the involvement of Nrf2 in cellular physiology1. Cell permeable.
分子式:C13H12ClNO3
分子量:265.70
溶剂:DMSO (15 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Nrf2 activator
Function / Pharmacology:A novel antioxidant response element (ARE) activator which activates Nrf2 by covalently modifying Keap1 (Kelch-like ECH-associated protein 1) a negative regulator of Nrf2. Modification of Cys151 of Keap1 by AI-1 disrupts the ability of Keap1 to searve as an adaptor for Cul3-Keap1 ubiquitin ligase complex, thereby stabilizing and inducing transcriptional activation of Nrf2. A useful pharmacological tool for probing the involvement of Nrf2 in cellular physiology1. Cell permeable.
