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YM-155
- 英文名称:YM-155
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10354
- cas:781661-94-7
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10354 |
用途 | 科研检测 |
英文名称 | YM-155 |
包装规格 | 1MG |
CAS编号 | 781661-94-7 |
别名 | YM-155 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C20H19BrN4O3
分子量:443.30
溶剂:DMSO (25 mg/ml)
性状:Tan to yellow solid
存储:-20°C
Activity (short version):Survivin inhibitor
Function / Pharmacology:A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
分子式:C20H19BrN4O3
分子量:443.30
溶剂:DMSO (25 mg/ml)
性状:Tan to yellow solid
存储:-20°C
Activity (short version):Survivin inhibitor
Function / Pharmacology:A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4