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Carfilzomib
- 英文名称:Carfilzomib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10356
- cas:868540-17-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10356 |
用途 | 科研检测 |
英文名称 | Carfilzomib |
包装规格 | 1MG |
CAS编号 | 868540-17-4 |
别名 | Carfilzomib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C40H57N5O7
分子量:719.93
溶剂:DMSO (80 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Proteasome inhibitor
Function / Pharmacology:A potent and irreversible proteasome inhibitor.1 Synthetic analog of the microbial product epoxomcin.2 Compared to bortezomib it displays equal potency but greater selectivity for the chymotrypsin-like activity of the proteasome. In cell culture it is more cytotoxic than bortezomib and hematologic tumor cells exhibit greater sensitivity than solid tumor cells. Treatment of cells with carfilzomib results in the accumulation of proteasome substrates and induction of cell cycle arrest and/or apoptosis.3 Effective against multiple myeloma.4 Active in vivo.
分子式:C40H57N5O7
分子量:719.93
溶剂:DMSO (80 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Proteasome inhibitor
Function / Pharmacology:A potent and irreversible proteasome inhibitor.1 Synthetic analog of the microbial product epoxomcin.2 Compared to bortezomib it displays equal potency but greater selectivity for the chymotrypsin-like activity of the proteasome. In cell culture it is more cytotoxic than bortezomib and hematologic tumor cells exhibit greater sensitivity than solid tumor cells. Treatment of cells with carfilzomib results in the accumulation of proteasome substrates and induction of cell cycle arrest and/or apoptosis.3 Effective against multiple myeloma.4 Active in vivo.