纯度:98% by TLC;NMR (Conforms)
分子式:C28H41NO3
分子量:439.63
溶剂:DMSO (50 mg/ml)
性状:Pale yellow viscous oil
存储:-80°C
Activity (short version):Endogenous TRPV1 activator
Function / Pharmacology:Endogenous conjugate of arachidonic acid and dopamine.1 May be the “endogenous capsaicin like substance” in the CNS acting at TRPV1 channels, EC50~ 50 nM1. Also acts as a selective cannabinoid CB1 agonist (Ki=0.25 and 15 ?M for CB1 and CB2 respectively)2 and results in a distinct signaling profile from any known cannabinoid3. Competitive inhibitor of FAAH and anadamide transport.4. Modulates acute systemic inflammation via non-hematopoietic TRPV1.5