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PR-619
- 英文名称：PR-619
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10364
- cas：2645-32-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10364 |
| 用途 | 科研检测 |
| 英文名称 | PR-619 |
| 包装规格 | 1MG |
| CAS编号 | 2645-32-1 |
| 别名 | PR-619 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C7H5N5S2
分子量:223.28
溶剂:DMSO (5 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):DUB inhibitor
Function / Pharmacology:PR-619 is a nonselective, reversible inhibitor of cysteine-reactive deubiquitinating enzymes (DUBs; 5-20 μM)1. PR-619 is highly useful for preserving ubiquitinated proteins during cell lysis. DUBs become unregulated in cell lysates and will act quickly to deubiquitinate proteins of interest during cell lysis. To preserve maximum amounts of ubiquitinated protein, include PR-619 (50-100 μM) in lysis buffers. PR-619 is also useful for interrogating the role of DUBs in intact cell systems2, and treatment of cells results in an overall accumulation of ubiquitinated proteins and many other phenotypes.
分子式:C7H5N5S2
分子量:223.28
溶剂:DMSO (5 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):DUB inhibitor
Function / Pharmacology:PR-619 is a nonselective, reversible inhibitor of cysteine-reactive deubiquitinating enzymes (DUBs; 5-20 μM)1. PR-619 is highly useful for preserving ubiquitinated proteins during cell lysis. DUBs become unregulated in cell lysates and will act quickly to deubiquitinate proteins of interest during cell lysis. To preserve maximum amounts of ubiquitinated protein, include PR-619 (50-100 μM) in lysis buffers. PR-619 is also useful for interrogating the role of DUBs in intact cell systems2, and treatment of cells results in an overall accumulation of ubiquitinated proteins and many other phenotypes.
