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Indirubin-3'-monoxime
- 英文名称:Indirubin-3'-monoxime
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10367
- cas:160807-49-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10367 |
用途 | 科研检测 |
英文名称 | Indirubin-3'-monoxime |
包装规格 | 1MG |
CAS编号 | 160807-49-8 |
别名 | Indirubin-3'-monoxime |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C16H11N3O2
分子量:277.29
溶剂:DMSO (6 mg/ml) Ethanol (4 mg/ml)
性状:Dark red or brown solid
存储:-20°C
Activity (short version):GSK-3b and CDK inhibitor
Function / Pharmacology:A potent GSK-3β inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer’s disease4. Cell permeable.
分子式:C16H11N3O2
分子量:277.29
溶剂:DMSO (6 mg/ml) Ethanol (4 mg/ml)
性状:Dark red or brown solid
存储:-20°C
Activity (short version):GSK-3b and CDK inhibitor
Function / Pharmacology:A potent GSK-3β inhibitor (IC50=22 nM)1. Also inhibits CDK1 (IC50=180 nM) and CDK5 (IC50=100 nM)1. Displays antimitotic properties and induces endoreplication following prophase arrest in HBL-100 cells2. Possesses antiangiogenic activity3. Attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer’s disease4. Cell permeable.