|
LY364947
- 英文名称：LY364947
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10369
- cas：396129-53-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10369 |
| 用途 | 科研检测 |
| 英文名称 | LY364947 |
| 包装规格 | 1MG |
| CAS编号 | 396129-53-6 |
| 别名 | LY364947 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC
分子式:C17H12N4
分子量:272.31
溶剂:DMSO (25 mg/ml)
性状:Beige solid
存储:RT
Activity (short version):ALK5 inhibitor
Function / Pharmacology:Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.
分子式:C17H12N4
分子量:272.31
溶剂:DMSO (25 mg/ml)
性状:Beige solid
存储:RT
Activity (short version):ALK5 inhibitor
Function / Pharmacology:Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.
