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LY364947
- 英文名称:LY364947
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10369
- cas:396129-53-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10369 |
用途 | 科研检测 |
英文名称 | LY364947 |
包装规格 | 1MG |
CAS编号 | 396129-53-6 |
别名 | LY364947 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC
分子式:C17H12N4
分子量:272.31
溶剂:DMSO (25 mg/ml)
性状:Beige solid
存储:RT
Activity (short version):ALK5 inhibitor
Function / Pharmacology:Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.
分子式:C17H12N4
分子量:272.31
溶剂:DMSO (25 mg/ml)
性状:Beige solid
存储:RT
Activity (short version):ALK5 inhibitor
Function / Pharmacology:Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable.