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AI-3
- 英文名称:AI-3
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10372
- cas:882288-28-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10372 |
用途 | 科研检测 |
英文名称 | AI-3 |
包装规格 | 1MG |
CAS编号 | 882288-28-0 |
别名 | AI-3 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C11H13ClO3S2
分子量:292.81
溶剂:DMSO (50 mg/ml) Ethanol (25 mg/ml)
性状:white solid MP = 71-74°C
存储:-20°C
Activity (short version):ARE activator
Function / Pharmacology:Activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo.
分子式:C11H13ClO3S2
分子量:292.81
溶剂:DMSO (50 mg/ml) Ethanol (25 mg/ml)
性状:white solid MP = 71-74°C
存储:-20°C
Activity (short version):ARE activator
Function / Pharmacology:Activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo.