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HIF-2α-I2
- 英文名称:HIF-2α-I2
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10380
- cas:1422955-31-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10380 |
用途 | 科研检测 |
英文名称 | HIF-2α-I2 |
包装规格 | 1MG |
CAS编号 | 1422955-31-4 |
别名 | HIF-2α-I2 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C12H6ClFN4O3
分子量:308.65
溶剂:DMSO (30 mg/ml) DMF (35 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):HIF-2α antagonist
Function / Pharmacology:Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2
分子式:C12H6ClFN4O3
分子量:308.65
溶剂:DMSO (30 mg/ml) DMF (35 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):HIF-2α antagonist
Function / Pharmacology:Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2