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Fascaplysin
- 英文名称:Fascaplysin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10388
- cas:114719-57-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10388 |
用途 | 科研检测 |
英文名称 | Fascaplysin |
包装规格 | 1MG |
CAS编号 | 114719-57-2 |
别名 | Fascaplysin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C18H11ClN2O4
分子量:306.75
溶剂:DMSO (20 mg/ml) water (2 mg/ml)
性状:Dark red-brown solid
存储:-20°C
Activity (short version):CDK4 inhibitor
Function / Pharmacology:A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.
分子式:C18H11ClN2O4
分子量:306.75
溶剂:DMSO (20 mg/ml) water (2 mg/ml)
性状:Dark red-brown solid
存储:-20°C
Activity (short version):CDK4 inhibitor
Function / Pharmacology:A novel marine natural product isolated from Thorectandra sp1. A potent and selective inhibitor of cyclin dependent kinase 4/cyclin D1 (IC50 = 0.35 μM) and is less selective for Cdk6/D1 (IC50 = 3.4 μM). Displays antiangiogenic acitivity2. Displays high cytotoxic activity against small cell lung cancer cell lines acting via multiple mechanisms including topoisomerase I, DNA integrity and ROS3.